EC Number   |
Protein Variants |
Reference |
|---|
    2.3.1.167 | D166A |
decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA |
755829 |
| 2.3.1.167 | D34E |
decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA |
755829 |
| 2.3.1.167 | D372E |
decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA |
755829 |
| 2.3.1.167 | D390H |
catalytic efficiency towards 10-deacetylbaccatin III and vinyl acetate is 96% of the wild-type value |
757640 |
| 2.3.1.167 | D390R |
catalytic efficiency towards 10-deacetylbaccatin III and vinyl acetate is improved by 2.3fold |
757640 |
| 2.3.1.167 | F160A |
mutation negatively affects activity |
757765 |
| 2.3.1.167 | F301A |
activity against 10-deacetyltaxol is 1.6times more active than wild-type activity, activitys against 10-deacetylbaccatin III is degraded |
757765 |
| 2.3.1.167 | F301V |
mutant enzyme is 2.85times more active against 10-deacetyltaxol than the wild-type enzyme |
757765 |
| 2.3.1.167 | F400A |
mutation negatively affects activity |
757765 |
| 2.3.1.167 | F44A |
activity against 10-deacetyltaxol is nearly undetectable |
757765 |
