EC Number |
Protein Variants |
Reference |
---|
2.1.1.202 | more |
generation of Arabidopsis thaliana T-DNA insertion mutants of potential mRNA m5C methyltransferases (RCMTs), and of single mutants of TRM4B, trm4b-3 and trm4b-4, the latter exhibit defects in root development. The fulllength transcript of TRM4B and its 3' fragment downstream of the T-DNA insertion sites are greatly decreased in trm4b-3 and undetectable in trm4b-4, implying that trm4b-3 and trm4b-4 could be reduction-of function and loss-of-function mutants, respectively |
757702 |
2.1.1.202 | more |
generation of NSUN2 knockout mice (homozygous Nsun2Gt[D014D11]Wrs) |
758103 |
2.1.1.202 | more |
generation of trm4a and trm4a/trm4b deletion mutants, tRNA methylome of wild-type, trm4aDELTA, trm4bDELTA, and trm4aDELTA/trm4bDELTA as determined by genome-wide high-throughput bisulfite sequencing, overview |
-, 757846 |
2.1.1.202 | more |
generation of trm4b and trm4a/trm4b deletion mutants, tRNA methylome of wild-type, trm4aDELTA, trm4bDELTA, and trm4aDELTA/trm4bDELTA as determined by genome-wide high-throughput bisulfite sequencing, overview |
-, 757846 |
2.1.1.202 | G679R |
naturally occuring mutation |
756866 |
2.1.1.202 | G679R |
naturally occurring mutation |
756866 |
2.1.1.202 | C424A |
organism containing the C424A mutation is not viable |
639472 |
2.1.1.202 | C478A |
organism containing the C478A mutation is viable |
639472 |
2.1.1.202 | more |
siRNA-mediated enzyme knockout in HeLa cells |
736856 |
2.1.1.202 | C271A |
site-directed mutagenesis, the mutant enzyme forms an irreversible covalent crosslink between itself and the methylated cytosine in its target RNA |
735907 |