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EC Number
Protein Variants
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1.8.4.8
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a mutant lacking glutathione reductase and glutaredoxins does barely grow on sulfate, strains containing a mutant C9S/C12S glutaredoxin grow poorly
659214
1.8.4.8
Q160L
mutant enzyme Gln160Leu is as active as the wild-type enzyme
133778
1.8.4.8
C239S
mutant enzymes Cys239Ser and Tyr209Phe are inactive
133778
1.8.4.8
Y209F
mutant enzymes Cys239Ser and Tyr209Phe are inactive
133778
1.8.4.8
K144A |
the mutation causes a 63000fold increase of kcat/KM and decreases the value of kmax by 270fold. Relative to the wild type enzyme, the affinity of adenosine 5-phosphosulfate for K144A is decreased by 400fold
712502
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