EC Number   |
Protein Variants |
Reference |
|---|
  1.14.99.58 | F117Y |
no change in regioselectivity |
661923 |
| 1.14.99.58 | F189A |
the heme degradation activity of the mutant is similar to that of the wild-type enzyme. The mutant produces only beta- and delta-biliverdins, but no alpha-biliverdin |
742737 |
| 1.14.99.58 | F189G |
the heme degradation activity of the mutant is similar to that of the wild-type enzyme. The mutant produces only beta- and delta-biliverdins, but no alpha-biliverdin |
742737 |
| 1.14.99.58 | F189L |
the heme degradation activity of the mutant is similar to that of the wild-type enzyme. The mutant produces only beta- and delta-biliverdins, but no alpha-biliverdin |
742737 |
| 1.14.99.58 | F189T |
the heme degradation activity of the mutant is similar to that of the wild-type enzyme. The mutant produces only beta- and delta-biliverdins, but no alpha-biliverdin |
742737 |
| 1.14.99.58 | G125V |
single-phase kinetics of transfer of heme from heme-binding protein PhuS |
678146 |
| 1.14.99.58 | H26A/K34A/K132A |
inactive |
742894 |
| 1.14.99.58 | K132A |
the heme degradation activity of the mutant is similar to that of the wild-type enzyme, but the mutant produces 12% of alpha-biliverdin in addition to the formation of normal beta- (26%) and delta- (62%) biliverdins |
742737 |
| 1.14.99.58 | K34A |
the heme degradation activity of the mutant is similar to that of the wild-type enzyme, but the mutant produces 11% of alpha-biliverdin in addition to the formation of normal beta- (34%) and delta- (55%) biliverdins |
742737 |
| 1.14.99.58 | K34A/K132A |
the heme degradation activity of the mutant is similar to that of the wild-type enzyme, but the mutant produces 18% of alpha-biliverdin in addition to the formation of normal beta- (27%) and delta- (56%) biliverdins |
742737 |
