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Results 1 - 10 of 18 > >>
EC Number
Protein Variants
Commentary
Reference
A318S
site-directed mutagenesis, the enzyme shows a marginal decrease in homospecific activity
A318S
the mutation does not influence enzyme activity
A348E
retained inside cell in a premature endoplasmic reticulum form, also naturally occuring mutation
C1021T
naturally occuring gene polymorphism, determination of the frequency in combat veterans with or without chronic posttraumatic stress disorder, overview
D100E
retained inside cell in a premature endoplasmic reticulum form, also naturally occuring mutation
D331N
retained inside cell in a premature endoplasmic reticulum form, also naturally occuring mutation
D460N
site-directed mutagenesis, the mutant shows reduced expression levels compared to the wild-type enzyme, the mutant shows reduced expression levels compared to the wild-type enzyme
G482R
the mutation has subsequent effect on the activity of the enzyme as it is present close to the active site
L208F
a natural variant - three phenotypes of enzyme isolated: 4 * L208-homoenzyme, 4 * F208-homoenzyme and 2 * F208, 2 * L208-heteroenzyme, no significant difference in kinetic properties
L317P
site-directed mutagenesis, the mutant shows secretory deficiency and is localized in the endoplasmic reticulum
Results 1 - 10 of 18 > >>