EC Number   |
Protein Variants  |
Reference |
|---|
   1.14.15.16 | A326G |
the mutant converts 1alpha-hydroxyvitamin-D3 into 1alpha,25-dihydroxyvitamin-D3-26,23-lactone |
717838 |
| 1.14.15.16 | A326G |
the mutation converts human CYP24A1 from 25-hydroxyvitamin-D3 24-hydroxylase into 25-hydroxyvitamin-D3 23-hydroxylase, generating 1alpha,25-dihydroxyvitamin D3-26,23-lactone |
716740 |
| 1.14.15.16 | E143del |
naturally occuring mutation |
736557 |
| 1.14.15.16 | E147del |
naturally occuring mutation |
736557 |
| 1.14.15.16 | E149del |
naturally occuring mutation |
736557 |
| 1.14.15.16 | E151X |
naturally occuring mutation |
736557 |
| 1.14.15.16 | E322K |
naturally occuring mutation |
736557 |
| 1.14.15.16 | I500F |
the mutant shows quite a different metabolism of 1alpha,25-dihydroxyvitamin D3 from both human and rat CYP24A1 |
716274 |
| 1.14.15.16 | I500L |
the mutant also shows the C-23 oxidation pathway |
716274 |
| 1.14.15.16 | I500T |
the mutant also shows the C-23 oxidation pathway |
716274 |
