EC Number   |
Protein Variants |
Reference |
|---|
    4.3.3.6 | E136A/R139A/R140A |
formation of an internal chromophore with characteristic absorbance at 320 nm during reaction (also observed with wild type protein) |
724239 |
| 4.3.3.6 | E15A |
mutant of Pdx2 (glutaminase subunit), 280% of the glutaminase activity compared to wild-type activity, Pdx2 (glutaminase subunit) complex with Pdx1 (pyridoxal 5'-phosphate synthase subunit) |
714170 |
| 4.3.3.6 | E48A |
mutant of Pdx2 (glutaminase subunit), no glutaminase activity in complex with Pdx1 (pyridoxal 5'-phosphate synthase subunit) |
714170 |
| 4.3.3.6 | H115A |
Pdx1 |
726269 |
| 4.3.3.6 | H115A/R138A |
Pdx1 |
726269 |
| 4.3.3.6 | H170N |
catalytically incompetent mutant of glutaminase subunit Pdx2 |
715491 |
| 4.3.3.6 | H170N |
Pdx2, catalytically inert |
726269 |
| 4.3.3.6 | H170N |
site-directed mutagenesis |
-, 729134 |
| 4.3.3.6 | H196N |
Pdx2, catalytically inactive |
726499 |
| 4.3.3.6 | H199N |
Pdx2 |
726499 |
