EC Number   |
Protein Variants |
Reference |
|---|
    4.3.1.17 | C385A |
inactive, mutants lacks the charge transfer absorbance at 400 nm that is indicative of the 4Fe-4S center |
713970 |
| 4.3.1.17 | C396A |
inactive, mutants lacks the charge transfer absorbance at 400 nm that is indicative of the 4Fe-4S center |
713970 |
| 4.3.1.17 | C458A |
44% of wild-type activity. Enzyme retains the positive cooperativity seen in the native enzyme |
713970 |
| 4.3.1.17 | C458A |
kcat/Km for L-serine is 2.2fold lower than the wild-type value |
746916 |
| 4.3.1.17 | cSDH-hSDH |
chimeric protein |
678411 |
| 4.3.1.17 | DELTA(C458) |
mutant enzyme has no detectable activity |
746916 |
| 4.3.1.17 | DELTA(P456,E457,C458) |
mutant enzyme has no detectable activity |
746916 |
| 4.3.1.17 | DELTAP128 |
hSDH |
678411 |
| 4.3.1.17 | E445A |
mutant enzyme has no detectable activity |
746916 |
| 4.3.1.17 | E457A |
kcat/Km for L-serine is 1.5fold lower than the wild-type value |
746916 |
