EC Number |
Protein Variants |
Reference |
---|
3.6.5.4 | N154A/E157A |
mutant |
644176 |
3.6.5.4 | N154I |
impaired nucleotide exchange |
644176 |
3.6.5.4 | N178K |
hydrolysis of XTP favored over GTP |
644180 |
3.6.5.4 | N178K |
site-directed mutagenesis of SRP54 (or SRbeta), the mutant shows a temperature-sensitive phenotype and weak binding of SRalpha |
757430 |
3.6.5.4 | N302A |
mutant, GTPase activation defective |
687905 |
3.6.5.4 | P142L |
reduced GTP hydrolysis, no effect on the interaction with FtsY |
658538 |
3.6.5.4 | P46A/Q47A/N48A/DELTAS49 |
mutant |
644176 |
3.6.5.4 | Q109A |
mutant, GTPase activation defective |
687905 |
3.6.5.4 | R140A |
site-directed mutagenesis, mutant cpSRP54 GTP-dependent complex assembly kinetics compared to the wild-type cpSRP54, overview |
718911 |
3.6.5.4 | R141A |
mutant, GTPase activation defective |
687905 |