EC Number   |
Protein Variants |
Reference |
|---|
   3.2.2.23 | S232E |
naturally occuring polymorphism, kinetics compared to the wild-type enzyme, overview |
708484 |
| 3.2.2.23 | S280E |
naturally occuring polymorphism, kinetics compared to the wild-type enzyme, overview |
708484 |
| 3.2.2.23 | S326C |
naturally occuring polymorphism, the mutant displays opposite-base specificity similar to that of wild-type OGG1. The mutant efficiently excises 8-oxoGua from oligodeoxynucleotides and 2,6-diamino-4-hydroxy-5-formamidopyrimidine from gamma-irradiated DNA, but excises 8-oxoG rather inefficiently from gamma-irradiated DNA |
708484 |
| 3.2.2.23 | S326E |
naturally occuring polymorphism, kinetics compared to the wild-type enzyme, overview |
708484 |
| 3.2.2.23 | Y170F |
mutation decreases Fpg binding but does not fully inactivate the protein |
750392 |
