Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Protein Variants

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

<< < Results 11 - 20 of 28 > >>
EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16I500V the mutant also shows the C-23 oxidation pathway 716274
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16L409S naturally occuring missense mutation, found on only one allele, no other mutation is found in exons or in at least 30 bp of each intron/exon junction. ThecL409S mutant has about 32% of wild-type 24-hydroxylase activity 736557
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16more development of truncated expression constructs for rat DELTA51CYP24A1. Adrenodoxin binding enhances the stability of the enzyme-substrate complex, despite lowering the ligand binding affinity of the free enzyme for calcitriol over 9fold. Truncation of CYP24A1's flexible N-terminus (DELTA51) improves the enzyme's ability to recruit substrate, without altering adrenodoxin's ability to stabilize the ligand-bound form 736701
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16more genotyping and phenotypes of diverse mutants of CYP24A1, overview 736557
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16more reconstitution of the metabolism of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] and the intermediates of the C24-oxidation pathway in a phospholipid-vesicle system. Changes to the phospholipid concentration do not affect the kinetic parameters for the metabolism of 1,25(OH)2D3 by CYP24A1, indicating that it is the concentration of substrates in the membrane phase that determines their rate of metabolism 736086
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16R159Q naturally occuring mutation 736557
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16R396W naturally occuring mutation 736557
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16S57D site-directed mutagenesis 736701
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16T416A the metabolic pattern by the mutant remains rat CYP24A1wild type 716274
Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.16T416F the mutant has reaction specificity similar to human CYP24A1 by also showing the C-23 oxidation pathway 716274
<< < Results 11 - 20 of 28 > >>