EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    5.3.99.3 | Aberrant Crypt Foci |
18451151 |
Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
4
4 |
| 5.3.99.3 | Aberrant Crypt Foci |
21986945 |
Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 5.3.99.3 | Aberrant Crypt Foci |
26611322 |
Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1. |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 5.3.99.3 | Acute Kidney Injury |
20844471 |
Amelioration of cisplatin nephrotoxicity by genetic or pharmacologic blockade of prostaglandin synthesis. |
ongoing research
unassigned |
3
0 |
| 5.3.99.3 | Acute Kidney Injury |
28860615 |
Aggravation of acute kidney injury by mPGES-2 down regulation is associated with autophagy inhibition and enhanced apoptosis. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
1
0 |
| 5.3.99.3 | Acute Kidney Injury |
30442945 |
Author Correction: Aggravation of acute kidney injury by mPGES-2 down regulation is associated with autophagy inhibition and enhanced apoptosis. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 5.3.99.3 | Acute Lung Injury |
34372885 |
Inhibition of microsomal prostaglandin E synthase-1 ameliorates acute lung injury in mice. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
3
3
0 |
| 5.3.99.3 | Adenocarcinoma |
2497497 |
Inhibition of GSH-dependent PGH2 isomerase in mammary adenocarcinoma cells by allicin. |
unassigned |
0 |
| 5.3.99.3 | Adenocarcinoma |
11592775 |
Expression of COX-2 and PGE synthase and synthesis of PGE(2)in endometrial adenocarcinoma: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors. |
causal interaction
diagnostic usage
unassigned |
2
4
0 |
| 5.3.99.3 | Adenocarcinoma |
12626523 |
Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
4 |
