EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
5.3.3.12 | Acute Kidney Injury |
30253909 |
D-dopachrome tautomerase predicts outcome but not the development of acute kidney injury after orthotopic liver transplantation. |
therapeutic application unassigned |
1 0 |
5.3.3.12 | Acute Lung Injury |
28840536 |
Astilbin alleviates sepsis-induced acute lung injury by inhibiting the expression of macrophage inhibitory factor in rats. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 2 3 |
5.3.3.12 | Adenocarcinoma |
21071513 |
The MIF homologue D-dopachrome tautomerase promotes COX-2 expression through ?-catenin-dependent and -independent mechanisms. |
causal interaction therapeutic application unassigned |
2 1 0 |
5.3.3.12 | Adenocarcinoma |
27434219 |
D-dopachrome tautomerase is over-expressed in pancreatic ductal adenocarcinoma and acts cooperatively with macrophage migration inhibitory factor to promote cancer growth. |
causal interaction unassigned |
4 0 |
5.3.3.12 | Adenoma |
29368299 |
Autophagic flux is essential for the downregulation of D-dopachrome tautomerase by atractylenolide I to ameliorate intestinal adenoma formation. |
causal interaction unassigned |
2 0 |
5.3.3.12 | Adenomyosis |
32719721 |
m6A RNA Methylation Regulators Contribute to Eutopic Endometrium and Myometrium Dysfunction in Adenomyosis. |
causal interaction diagnostic usage unassigned |
3 1 0 |
5.3.3.12 | Albinism |
8433006 |
White mutants in mice shedding light on humans. |
causal interaction unassigned |
3 0 |
5.3.3.12 | Albinism, Oculocutaneous |
23764898 |
Reduced glutathione disrupts the intracellular trafficking of tyrosinase and tyrosinase-related protein-1 but not dopachrome tautomerase and Pmel17 to melanosomes, which results in the attenuation of melanization. |
therapeutic application unassigned |
1 0 |
5.3.3.12 | Albinism, Oculocutaneous |
25396269 |
A closer look at evolution: Variants (SNPs) of genes involved in skin pigmentation, including EXOC2, TYR, TYRP1, and DCT, are associated with 25(OH)D serum concentration. |
diagnostic usage ongoing research unassigned |
1 1 0 |
5.3.3.12 | Albinism, Oculocutaneous |
33100333 |
Dopachrome tautomerase variants in patients with oculocutaneous albinism. |
causal interaction therapeutic application unassigned |
3 1 0 |