EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    4.2.1.19 | Dehydration |
26095028 |
Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. |
unassigned |
0 |
| 4.2.1.19 | Infections |
26854126 |
Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
2
1
0 |
| 4.2.1.19 | Starvation |
11162372 |
Cryptosporidium parvum: functional complementation of a parasite transcriptional coactivator CpMBF1 in yeast. |
unassigned |
0 |
| 4.2.1.19 | Starvation |
26854126 |
Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
2
1
0 |
| 4.2.1.19 | Tuberculosis |
22102255 |
HisB from Mycobacterium tuberculosis: cloning, overexpression in Mycobacterium smegmatis, purification, crystallization and preliminary X-ray crystallographic analysis. |
unassigned |
0 |
| 4.2.1.19 | Tuberculosis |
24311587 |
Structures of native, substrate-bound and inhibited forms of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase. |
ongoing research
unassigned |
2
0 |
| 4.2.1.19 | Tuberculosis |
34288118 |
Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase. |
ongoing research
therapeutic application
unassigned |
4
4
0 |
