EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
4.1.2.27 | Acute Lung Injury |
21148740 |
Protection of LPS-Induced Murine Acute Lung Injury by Sphingosine-1-Phosphate Lyase Suppression. |
ongoing research therapeutic application unassigned |
2 1 0 |
4.1.2.27 | Acute Lung Injury |
27720306 |
Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. |
unassigned |
0 |
4.1.2.27 | Addison Disease |
28165343 |
Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome. |
diagnostic usage unassigned |
2 0 |
4.1.2.27 | Addison Disease |
29685115 |
Acquired modification of sphingosine-1-phosphate lyase activity is not related to adrenal insufficiency. |
causal interaction therapeutic application unassigned |
4 2 0 |
4.1.2.27 | Addison Disease |
30090628 |
Nephrotic syndrome and adrenal insufficiency caused by a variant in SGPL1. |
causal interaction ongoing research unassigned |
3 2 0 |
4.1.2.27 | Addison Disease |
30517686 |
SGPL1 Deficiency: A Rare Cause of Primary Adrenal Insufficiency. |
causal interaction unassigned |
4 0 |
4.1.2.27 | Addison Disease |
32322566 |
A Sphingosine-1-Phosphate Lyase Mutation Associated With Congenital Nephrotic Syndrome and Multiple Endocrinopathy. |
causal interaction diagnostic usage unassigned |
3 2 0 |
4.1.2.27 | Addison Disease |
32682944 |
Sphingosine-1-phosphate lyase (SGPL1) deficiency is associated with mitochondrial dysfunction. |
causal interaction ongoing research unassigned |
4 3 0 |
4.1.2.27 | Adenocarcinoma |
31409741 |
High FA2H and UGT8 transcript levels predict hydroxylated hexosylceramide accumulation in lung adenocarcinoma. |
causal interaction diagnostic usage unassigned |
4 2 0 |
4.1.2.27 | Adrenal Insufficiency |
28165339 |
Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. |
causal interaction unassigned |
4 0 |