EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    4.1.1.36 | Atherosclerosis |
29482039 |
A genetic association study of carotid intima-media thickness (CIMT) and plaque in Mexican Americans and European Americans with rheumatoid arthritis. |
causal interaction
unassigned |
1
0 |
| 4.1.1.36 | Infections |
27676316 |
Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
3
4
0 |
| 4.1.1.36 | phosphopantothenoylcysteine decarboxylase deficiency |
21551303 |
Pantethine rescues phosphopantothenoylcysteine synthetase and phosphopantothenoylcysteine decarboxylase deficiency in Escherichia coli but not in Pseudomonas aeruginosa. |
therapeutic application
unassigned |
1
0 |
| 4.1.1.36 | Pulmonary Disease, Chronic Obstructive |
19266201 |
Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1. |
therapeutic application
unassigned |
1
0 |
| 4.1.1.36 | Tuberculosis |
27676316 |
Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
3
4
0 |
| 4.1.1.36 | Tuberculosis |
32206243 |
Overcoming synthetic challenges in targeting coenzyme A biosynthesis with the antimicrobial natural product CJ-15,801. |
therapeutic application
unassigned |
1
0 |
| 4.1.1.36 | Tuberculosis |
33420031 |
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. |
therapeutic application
unassigned |
1
0 |
| 4.1.1.36 | Tuberculosis |
33939919 |
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity. |
therapeutic application
unassigned |
1
0 |
