EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.6.1.62 | 5'-(n7-methylguanosine 5'-triphospho)-[mrna] hydrolase deficiency |
33947817 |
CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 3.6.1.62 | Infections |
26038567 |
Virus-induced translational arrest through 4EBP1/2-dependent decay of 5'-TOP mRNAs restricts viral infection. |
unassigned |
0 |
| 3.6.1.62 | Mental Retardation, X-Linked |
17157254 |
Identification of an mRNA-decapping regulator implicated in X-linked mental retardation. |
ongoing research
therapeutic application
unassigned |
2
2
0 |
| 3.6.1.62 | Muscular Atrophy, Spinal |
25959423 |
A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS. |
therapeutic application
unassigned |
3
0 |
| 3.6.1.62 | Poxviridae Infections |
24155373 |
The D10 decapping enzyme of vaccinia virus contributes to decay of cellular and viral mRNAs and to virulence in mice. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
1
0 |
| 3.6.1.62 | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
28344317 |
Epigenetic loss of the RNA decapping enzyme NUDT16 mediates C-MYC activation in T-cell acute lymphoblastic leukemia. |
causal interaction
ongoing research
unassigned |
2
3
0 |
| 3.6.1.62 | Thyroid Neoplasms |
33816259 |
Comprehensive Analysis of the Functions and Prognostic Value of RNA-Binding Proteins in Thyroid Cancer. |
diagnostic usage
ongoing research
unassigned |
2
3
0 |
| 3.6.1.62 | Vaccinia |
9847390 |
Down regulation of gene expression by the vaccinia virus D10 protein. |
ongoing research
unassigned |
3
0 |
| 3.6.1.62 | Vaccinia |
16378957 |
Characterization of a vaccinia virus mutant with a deletion of the D10R gene encoding a putative negative regulator of gene expression. |
unassigned |
0 |
| 3.6.1.62 | Vaccinia |
17283339 |
Vaccinia virus D10 protein has mRNA decapping activity, providing a mechanism for control of host and viral gene expression. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
1
1
0 |
