EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.B50 | Bone Resorption |
15906014 |
Different cysteine proteinases involved in bone resorption and osteoclast formation. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
3
3
0 |
| 3.4.22.B50 | Bronchitis |
9636369 |
Characterization of the two overlapping papain-like proteinase domains encoded in gene 1 of the coronavirus infectious bronchitis virus and determination of the C-terminal cleavage site of an 87-kDa protein. |
ongoing research
unassigned |
3
0 |
| 3.4.22.B50 | Bronchitis |
10644337 |
Identification of a novel cleavage activity of the first papain-like proteinase domain encoded by open reading frame 1a of the coronavirus Avian infectious bronchitis virus and characterization of the cleavage products. |
ongoing research
unassigned |
1
0 |
| 3.4.22.B50 | Carcinoma |
19166818 |
Crystal structure of SCCA1 and insight about the interaction with JNK1. |
therapeutic application
unassigned |
1
0 |
| 3.4.22.B50 | Carcinoma, Squamous Cell |
19166818 |
Crystal structure of SCCA1 and insight about the interaction with JNK1. |
therapeutic application
unassigned |
1
0 |
| 3.4.22.B50 | Coronavirus Infections |
25746232 |
Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV. |
unassigned |
0 |
| 3.4.22.B50 | COVID-19 |
33251371 |
Structure-based drug designing of naphthalene based SARS-CoV PLpro inhibitors for the treatment of COVID-19. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 3.4.22.B50 | Drug-Related Side Effects and Adverse Reactions |
34513113 |
Nanoparticles of ZnO/Berberine complex contract COVID-19 and respiratory co-bacterial infection in addition to elimination of hydroxychloroquine toxicity. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
1
1
0 |
| 3.4.22.B50 | Foot-and-Mouth Disease |
12228254 |
Recognition of eukaryotic initiation factor 4G isoforms by picornaviral proteinases. |
unassigned |
0 |
| 3.4.22.B50 | Foot-and-Mouth Disease |
12297280 |
Foot-and-mouth disease virus leader proteinase: a papain-like enzyme requiring an acidic environment in the active site. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
