EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.63 | Adenoma |
18716417 |
Clinicopathological significance of caspase-8 and caspase-10 expression in rectal cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 3.4.22.63 | Airway Obstruction |
18823309 |
Association of polymorphisms in CASP10 and CASP8 with FEV/FVC and bronchial hyperresponsiveness in ethnically diverse asthmatics. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 3.4.22.63 | Anemia, Hemolytic, Autoimmune |
21382177 |
Exonic deletion of CASP10 in a patient presenting with systemic juvenile idiopathic arthritis, but not with autoimmune lymphoproliferative syndrome type IIa. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 3.4.22.63 | Arthritis |
21382177 |
Exonic deletion of CASP10 in a patient presenting with systemic juvenile idiopathic arthritis, but not with autoimmune lymphoproliferative syndrome type IIa. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 3.4.22.63 | Arthritis, Juvenile |
21382177 |
Exonic deletion of CASP10 in a patient presenting with systemic juvenile idiopathic arthritis, but not with autoimmune lymphoproliferative syndrome type IIa. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 3.4.22.63 | Asthma |
18823309 |
Association of polymorphisms in CASP10 and CASP8 with FEV/FVC and bronchial hyperresponsiveness in ethnically diverse asthmatics. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 3.4.22.63 | Autoimmune Lymphoproliferative Syndrome |
10412980 |
Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II. |
diagnostic usage
ongoing research
unassigned |
3
2
0 |
| 3.4.22.63 | Autoimmune Lymphoproliferative Syndrome |
11397650 |
Mutations in apoptosis genes: a pathogenetic factor for human disease. |
causal interaction
unassigned |
1
0 |
| 3.4.22.63 | Autoimmune Lymphoproliferative Syndrome |
11717445 |
Caspase-10 is an initiator caspase in death receptor signaling. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
1
4
0 |
| 3.4.22.63 | Autoimmune Lymphoproliferative Syndrome |
12010812 |
Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas. |
causal interaction
ongoing research
unassigned |
3
2
0 |
