EC Number   |
Disease |
PubMed ID  |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.49 | Herpes Zoster |
16839882 |
Resolution of chiasmata in oocytes requires separase-mediated proteolysis. |
ongoing research
unassigned |
1
0 |
| 3.4.22.49 | Carcinogenesis |
17210788 |
A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. |
causal interaction
unassigned |
3
0 |
| 3.4.22.49 | Neoplasms |
17210788 |
A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. |
causal interaction
unassigned |
3
0 |
| 3.4.22.49 | Carcinoma |
18616699 |
Effect of separase depletion on ionizing radiation-induced cell cycle checkpoints and survival in human lung cancer cell lines. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 3.4.22.49 | Carcinoma, Non-Small-Cell Lung |
18616699 |
Effect of separase depletion on ionizing radiation-induced cell cycle checkpoints and survival in human lung cancer cell lines. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 3.4.22.49 | Lung Neoplasms |
18616699 |
Effect of separase depletion on ionizing radiation-induced cell cycle checkpoints and survival in human lung cancer cell lines. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 3.4.22.49 | Breast Neoplasms |
18728194 |
Overexpression of Separase induces aneuploidy and mammary tumorigenesis. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
1
0 |
| 3.4.22.49 | Carcinogenesis |
18728194 |
Overexpression of Separase induces aneuploidy and mammary tumorigenesis. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
1
0 |
| 3.4.22.49 | Neoplasms |
18728194 |
Overexpression of Separase induces aneuploidy and mammary tumorigenesis. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
1
0 |
| 3.4.22.49 | Breast Neoplasms |
19008095 |
Single nucleotide polymorphisms in chromosomal instability genes and risk and clinical outcome of breast cancer: a Swedish prospective case-control study. |
diagnostic usage
ongoing research
unassigned |
4
3
0 |
