EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.36 | Acidosis |
26715049 |
Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons. |
unassigned |
0 |
| 3.4.22.36 | Acidosis |
30487596 |
The role of Ca2+ in acid-sensing ion channel 1a-mediated chondrocyte pyroptosis in rat adjuvant arthritis. |
unassigned |
0 |
| 3.4.22.36 | Acidosis |
32678496 |
Acid-sensing ion channel 1a mediates acid-induced pyroptosis through calpain-2/calcineurin pathway in rat articular chondrocytes. |
causal interaction
unassigned |
2
0 |
| 3.4.22.36 | Acne Vulgaris |
23884315 |
Propionibacterium acnes Induces IL-1? Secretion via the NLRP3 Inflammasome in Human Monocytes. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
1
1
0 |
| 3.4.22.36 | Acne Vulgaris |
29648825 |
Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne. |
therapeutic application
unassigned |
4
0 |
| 3.4.22.36 | Acquired Immunodeficiency Syndrome |
11122242 |
Apoptosis and apoptosis-associated perturbations of peripheral blood lymphocytes during HIV infection: comparison between AIDS patients and asymptomatic long-term non-progressors. |
causal interaction
diagnostic usage
unassigned |
1
3
0 |
| 3.4.22.36 | Acute Coronary Syndrome |
15364800 |
Different quantitative apoptotic traits in coronary atherosclerotic plaques from patients with stable angina pectoris and acute coronary syndromes. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
1
2
0 |
| 3.4.22.36 | Acute Coronary Syndrome |
27129183 |
Colchicine therapy in acute coronary syndrome patients acts on caspase-1 to suppress NLRP3 inflammasome monocyte activation. |
therapeutic application
unassigned |
1
0 |
| 3.4.22.36 | Acute Coronary Syndrome |
28456882 |
The NLRP3 and CASP1 gene polymorphisms are associated with developing of acute coronary syndrome: a case-control study. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
1
1
0 |
| 3.4.22.36 | Acute Kidney Injury |
11342578 |
Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. |
ongoing research
unassigned |
4
0 |
