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EC Number Disease PubMed ID Title of Publication Category Confidence Level
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Adenocarcinoma 9166946 Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours. causal interaction
diagnostic usage
ongoing research
unassigned
3
3
2
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Adenocarcinoma 28347547 PACE4 is an important driver of ZR-75-1 estrogen receptor-positive breast cancer proliferation and tumor progression. causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
4
4
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Anemia 18664504 Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7. causal interaction
therapeutic application
unassigned
3
4
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Anthrax 9234799 A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen. causal interaction
ongoing research
therapeutic application
unassigned
3
1
2
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Anthrax 10215603 Endoprotease PACE4 is Ca2+-dependent and temperature-sensitive and can partly rescue the phenotype of a furin-deficient cell strain. therapeutic application
unassigned
1
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Breast Neoplasms 9185698 Pro-protein convertase gene expression in human breast cancer. diagnostic usage
ongoing research
unassigned
3
4
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Breast Neoplasms 17909005 Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells' malignant phenotypes: role of tissue inhibitors of metalloproteinase-1. ongoing research
therapeutic application
unassigned
1
1
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Breast Neoplasms 25333574 PACE4 regulates proliferation, migration and invasion in human breast cancer MDA-MB-231 cells. causal interaction
ongoing research
therapeutic application
unassigned
4
4
4
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Breast Neoplasms 28347547 PACE4 is an important driver of ZR-75-1 estrogen receptor-positive breast cancer proliferation and tumor progression. causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
4
4
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B25Carcinogenesis 9393739 Expression of PACE4 in chemically induced carcinomas is associated with spindle cell tumor conversion and increased invasive ability. causal interaction
ongoing research
therapeutic application
unassigned
4
4
1
0
Results 1 - 10 of 120 > >>