EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.93 | Adrenal Insufficiency |
14617756 |
Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency. |
ongoing research
unassigned |
2
0 |
| 3.4.21.93 | Carcinogenesis |
20052009 |
Targeted production of proprotein convertase PC1 enhances mammary development and tumorigenesis in transgenic mice. |
causal interaction
ongoing research
unassigned |
1
3
0 |
| 3.4.21.93 | Carcinoid Tumor |
1547893 |
Expression in human lung tumor cells of the proprotein processing enzyme PC1/PC3. Cloning and primary sequence of a 5 kb cDNA. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
3
4
0 |
| 3.4.21.93 | Coronary Artery Disease |
24489861 |
Genetic variants in PCSK1 gene are associated with the risk of coronary artery disease in type 2 diabetes in a Chinese Han population: a case control study. |
causal interaction
diagnostic usage
unassigned |
1
1
0 |
| 3.4.21.93 | Cushing Syndrome |
27766686 |
Treatment-related neuroendocrine prostate cancer resulting in Cushing's syndrome. |
causal interaction
diagnostic usage
unassigned |
4
4
0 |
| 3.4.21.93 | Diabetes Insipidus |
23800642 |
Severe obesity and diabetes insipidus in a patient with PCSK1 deficiency. |
causal interaction
unassigned |
4
0 |
| 3.4.21.93 | Diabetes Insipidus |
24280991 |
Exome sequencing finds a novel PCSK1 mutation in a child with generalized malabsorptive diarrhea and diabetes insipidus. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 3.4.21.93 | Diabetes Insipidus, Neurogenic |
23800642 |
Severe obesity and diabetes insipidus in a patient with PCSK1 deficiency. |
causal interaction
unassigned |
4
0 |
| 3.4.21.93 | Diabetes Mellitus |
21437630 |
Association of type 2 diabetes susceptibility genes (TCF7L2, SLC30A8, PCSK1 and PCSK2) and proinsulin conversion in a Chinese population. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
2
1
0 |
| 3.4.21.93 | Diabetes Mellitus, Type 2 |
8666140 |
Human prohormone convertase 3 gene: exon-intron organization and molecular scanning for mutations in Japanese subjects with NIDDM. |
diagnostic usage
ongoing research
unassigned |
1
1
0 |
