EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.109 | Acidosis |
19940125 |
Matriptase activation, an early cellular response to acidosis. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
3
0 |
| 3.4.21.109 | Acidosis |
26157007 |
Matriptase activation and shedding through PDGF-D-mediated extracellular acidosis. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
4
2
0 |
| 3.4.21.109 | Adenocarcinoma |
14584072 |
The novel serine protease tumor-associated differentially expressed gene-15 (matriptase/MT-SP1) is highly overexpressed in cervical carcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
4 |
| 3.4.21.109 | Adenocarcinoma |
15471558 |
Paradoxically enhanced immunoreactivity of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in cancer cells at the invasion front. |
unassigned |
0 |
| 3.4.21.109 | Adenocarcinoma |
16439987 |
Increasing expression of serine protease matriptase in ovarian tumors: tissue microarray analysis of immunostaining score with clinicopathological parameters. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
3 |
| 3.4.21.109 | Adenocarcinoma |
16467405 |
Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
4
1 |
| 3.4.21.109 | Adenocarcinoma |
16492908 |
A novel biomarker for staging human prostate adenocarcinoma: overexpression of matriptase with concomitant loss of its inhibitor, hepatocyte growth factor activator inhibitor-1. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 3.4.21.109 | Adenocarcinoma |
18274158 |
Decreased matriptase/HAI-1 ratio in advanced colorectal adenocarcinoma of Chinese patients. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
3
4 |
| 3.4.21.109 | Adenocarcinoma |
18338334 |
The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
4
0 |
| 3.4.21.109 | Adenocarcinoma |
19578749 |
Use of IHC and newly designed matriptase inhibitors to elucidate the role of matriptase in pancreatic ductal adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
3 |
