EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.18.1 | Acquired Immunodeficiency Syndrome |
28078176 |
The function of cathepsins B, D, and X in atherosclerosis. |
therapeutic application
unassigned |
1
0 |
| 3.4.18.1 | Adenocarcinoma |
15162377 |
Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
4
1
0 |
| 3.4.18.1 | Alagille Syndrome |
30087368 |
Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis. |
causal interaction
diagnostic usage
unassigned |
1
3
0 |
| 3.4.18.1 | Alzheimer Disease |
23621429 |
Neuroprotective role of ?-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X. |
unassigned |
0 |
| 3.4.18.1 | Alzheimer Disease |
30459560 |
Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1?E9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease. |
causal interaction
ongoing research
unassigned |
1
4
0 |
| 3.4.18.1 | Bone Diseases, Metabolic |
31278293 |
Cathepsin Z as a novel potential biomarker for osteoporosis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
3
4 |
| 3.4.18.1 | Breast Neoplasms |
20133781 |
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 3.4.18.1 | Carcinogenesis |
15162377 |
Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
4
1
0 |
| 3.4.18.1 | Carcinogenesis |
16025436 |
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
1
4
0 |
| 3.4.18.1 | Carcinogenesis |
23152410 |
IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
