EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.99.B1 | Acquired Immunodeficiency Syndrome |
12126622 |
A conserved tyrosine residue aids ternary complex formation, but not catalysis, in phage T5 flap endonuclease. |
unassigned |
0 |
| 3.1.99.B1 | Adenomatous Polyposis Coli |
22787431 |
Adenomatous polyposis coli interacts with flap endonuclease 1 to block its nuclear entry and function. |
therapeutic application
unassigned |
1
0 |
| 3.1.99.B1 | Adenomatous Polyposis Coli |
27088617 |
Interaction between APC and Fen1 during breast carcinogenesis. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
1
1
0 |
| 3.1.99.B1 | Ataxia Telangiectasia |
25111287 |
Is there a role for base excision repair in estrogen/estrogen receptor-driven breast cancers? |
diagnostic usage
ongoing research
unassigned |
1
3
0 |
| 3.1.99.B1 | Bloom Syndrome |
14688284 |
Stimulation of flap endonuclease-1 by the Bloom's syndrome protein. |
unassigned |
0 |
| 3.1.99.B1 | Bloom Syndrome |
16326861 |
The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.1.99.B1 | Breast Neoplasms |
24486718 |
Curcumin inhibits proliferation of breast cancer cells through Nrf2-mediated down-regulation of Fen1 expression. |
causal interaction
unassigned |
3
0 |
| 3.1.99.B1 | Breast Neoplasms |
25111287 |
Is there a role for base excision repair in estrogen/estrogen receptor-driven breast cancers? |
diagnostic usage
ongoing research
unassigned |
1
3
0 |
| 3.1.99.B1 | Breast Neoplasms |
27088617 |
Interaction between APC and Fen1 during breast carcinogenesis. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
1
1
0 |
| 3.1.99.B1 | Breast Neoplasms |
27801669 |
FEN1 gene variants confer reduced risk of breast cancer in chinese women: A case-control study. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
2
1
0 |
