EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.5.B1 | Adenocarcinoma of Lung |
25449277 |
SAMHD1 is down regulated in lung cancer by methylation and inhibits tumor cell proliferation. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
2
0 |
| 3.1.5.B1 | Adenocarcinoma of Lung |
33569199 |
SAMHD1 can suppress lung adenocarcinoma progression through the negative regulation of STING. |
diagnostic usage
unassigned |
2
0 |
| 3.1.5.B1 | Anemia |
23158101 |
Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
2
1
1
3 |
| 3.1.5.B1 | Anemia |
25010268 |
Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
4
2
0 |
| 3.1.5.B1 | Anemia |
30181218 |
Interplay of ancestral non-primate lentiviruses with the virus-restricting SAMHD1 proteins of their hosts. |
unassigned |
0 |
| 3.1.5.B1 | Anemia |
33172327 |
Equine lentivirus counteracts SAMHD1 restriction by Rev-mediated degradation of SAMHD1 via the BECN1-dependent lysosomal pathway. |
ongoing research
unassigned |
1
0 |
| 3.1.5.B1 | Aneurysm |
28289923 |
Tocilizumab reverses cerebral vasculopathy in a patient with homozygous SAMHD1 mutation. |
unassigned |
0 |
| 3.1.5.B1 | Arbovirus Infections |
30959732 |
SAMHD1 Enhances Chikungunya and Zika Virus Replication in Human Skin Fibroblasts. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 3.1.5.B1 | Atherosclerosis |
26504826 |
SAMHD1 Gene Mutations Are Associated with Cerebral Large-Artery Atherosclerosis. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.1.5.B1 | Autoimmune Diseases |
22174685 |
SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
1
0 |
