EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.3.17 | Adenocarcinoma of Lung |
11801602 |
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
2
1
0 |
| 3.1.3.17 | Adenoma |
19765110 |
Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
3
2 |
| 3.1.3.17 | Adenomatous Polyposis Coli |
11836553 |
Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays. |
ongoing research
unassigned |
1
0 |
| 3.1.3.17 | African Swine Fever |
17215279 |
The MyD116 African swine fever virus homologue interacts with the catalytic subunit of protein phosphatase 1 and activates its phosphatase activity. |
diagnostic usage
unassigned |
3
0 |
| 3.1.3.17 | African Swine Fever |
20702639 |
The African swine fever virus DP71L protein recruits the protein phosphatase 1 catalytic subunit to dephosphorylate eIF2alpha and inhibits CHOP induction but is dispensable for these activities during virus infection. |
unassigned |
0 |
| 3.1.3.17 | African Swine Fever |
28189088 |
Identification of residues within the African swine fever virus DP71L protein required for dephosphorylation of translation initiation factor eIF2? and inhibiting activation of pro-apoptotic CHOP. |
therapeutic application
unassigned |
1
0 |
| 3.1.3.17 | Alzheimer Disease |
7517023 |
Dephosphorylation of tau protein from Alzheimer's disease patients. |
diagnostic usage
ongoing research
unassigned |
1
1
0 |
| 3.1.3.17 | Alzheimer Disease |
8137929 |
Dephosphorylation of microtubule-associated protein tau by protein phosphatase-1 and -2C and its implication in Alzheimer disease. |
causal interaction
unassigned |
4
0 |
| 3.1.3.17 | Alzheimer Disease |
15894402 |
CAT 53: a protein phosphatase 1 nuclear targeting subunit encoded in the MHC Class I region strongly expressed in regions of the brain involved in memory, learning, and Alzheimer's disease. |
causal interaction
unassigned |
2
0 |
| 3.1.3.17 | Alzheimer Disease |
31951013 |
Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease. |
causal interaction
unassigned |
4
0 |
