EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.1.89 | Adenocarcinoma |
26377365 |
Protein phosphatase methylesterase-1 (PME-1) expression predicts a favorable clinical outcome in colorectal cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
2 |
| 3.1.1.89 | Alzheimer Disease |
21639134 |
Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
unassigned |
0 |
| 3.1.1.89 | Carcinoma |
32351291 |
DNAH17-AS1 promotes pancreatic carcinoma by increasing PPME1 expression via inhibition of miR-432-5p. |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
4
4
0 |
| 3.1.1.89 | Choriocarcinoma |
23911878 |
IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1. |
unassigned |
0 |
| 3.1.1.89 | Colorectal Neoplasms |
26377365 |
Protein phosphatase methylesterase-1 (PME-1) expression predicts a favorable clinical outcome in colorectal cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
2 |
| 3.1.1.89 | Glioblastoma |
24253382 |
Genetic amplification of PPME1 in gastric and lung cancer and its potential as a novel therapeutic target. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
3
4 |
| 3.1.1.89 | Lung Neoplasms |
24253382 |
Genetic amplification of PPME1 in gastric and lung cancer and its potential as a novel therapeutic target. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
3
4 |
| 3.1.1.89 | Neoplasms |
21398589 |
Organic Synthesis Toward Small-Molecule Probes and Drugs Special Feature: Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors. |
therapeutic application
unassigned |
1
0 |
| 3.1.1.89 | Neoplasms |
21639134 |
Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. |
unassigned |
0 |
| 3.1.1.89 | Neoplasms |
24059230 |
Recent Trends in the Design, Synthesis and Biological Exploration of ?-Lactams. |
ongoing research
unassigned |
3
0 |
