EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.8.2.8 | Albuminuria |
24759151 |
Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 2.8.2.8 | Amyotrophic Lateral Sclerosis |
34435379 |
NDST3 deacetylates ?-tubulin and suppresses V-ATPase assembly and lysosomal acidification. |
causal interaction
unassigned |
1
0 |
| 2.8.2.8 | Anophthalmos |
17107998 |
Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 2.8.2.8 | Asthma |
24794009 |
Endothelial and leukocyte heparan sulfates regulate the development of allergen-induced airway remodeling in a mouse model. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 2.8.2.8 | Ataxia |
28211985 |
A girl with developmental delay, ataxia, cranial nerve palsies, severe respiratory problems in infancy-Expanding NDST1 syndrome. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
1
1
0 |
| 2.8.2.8 | Breast Neoplasms |
25156775 |
Methylation-regulated miR-149 modulates chemoresistance by targeting GlcNAc N-deacetylase/N-sulfotransferase-1 in human breast cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
1
1 |
| 2.8.2.8 | Carcinoma |
21947487 |
MicroRNA-191 targets N-deacetylase/N-sulfotransferase 1 and promotes cell growth in human gastric carcinoma cell line MGC803. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 2.8.2.8 | Carcinoma |
27237321 |
Glycan Sulfation Modulates Dendritic Cell Biology and Tumor Growth. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 2.8.2.8 | Carcinoma |
27543953 |
Heparan sulfate proteoglycans mediate renal carcinoma metastasis. |
diagnostic usage
ongoing research
unassigned |
3
3
0 |
| 2.8.2.8 | Carcinoma |
30820959 |
IDUA, NDST1, SAP30L, CRYBA4, and SI as novel prognostic signatures clear cell renal cell carcinoma. |
therapeutic application
unassigned |
1
0 |
