EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.7.7.1 | Adenocarcinoma of Lung |
33392072 |
Mitochondrial Deoxyguanosine Kinase Regulates NAD+ Biogenesis Independent of Mitochondria Complex I Activity. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
4
0 |
| 2.7.7.1 | Alzheimer Disease |
19778564 |
Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity. |
ongoing research
unassigned |
2
0 |
| 2.7.7.1 | Alzheimer Disease |
29175372 |
NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
1
0 |
| 2.7.7.1 | Alzheimer Disease |
33447901 |
Nmnat1 Modulates Mitochondrial Oxidative Stress by Inhibiting Caspase-3 Signaling in Alzheimer's Disease. |
causal interaction
unassigned |
4
0 |
| 2.7.7.1 | Anemia, Hemolytic |
24739386 |
Deficiency of nicotinamide mononucleotide adenylyltransferase 3 (nmnat3) causes hemolytic anemia by altering the glycolytic flow in mature erythrocytes. |
causal interaction
unassigned |
4
0 |
| 2.7.7.1 | Anemia, Hemolytic |
26756334 |
Nmnat3 Is Dispensable in Mitochondrial NAD Level Maintenance In Vivo. |
causal interaction
ongoing research
unassigned |
1
1
0 |
| 2.7.7.1 | Blindness |
22842227 |
NMNAT1 mutations cause Leber congenital amaurosis. |
causal interaction
unassigned |
3
0 |
| 2.7.7.1 | Blindness |
22842229 |
Mutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophy. |
causal interaction
unassigned |
4
0 |
| 2.7.7.1 | Blindness |
22842230 |
Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration. |
causal interaction
unassigned |
3
0 |
| 2.7.7.1 | Blindness |
22842231 |
Exome sequencing identifies NMNAT1 mutations as a cause of Leber congenital amaurosis. |
causal interaction
unassigned |
2
0 |
