EC Number   |
Disease |
PubMed ID  |
Title of Publication |
Category |
Confidence Level |
|---|
   2.7.11.27 | Carcinoma, Hepatocellular |
11554766 |
Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line. |
ongoing research
unassigned |
3
0 |
| 2.7.11.27 | Infections |
17098823 |
Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy. |
causal interaction
unassigned |
1
0 |
| 2.7.11.27 | Mitochondrial Diseases |
17332500 |
Diverse cytopathologies in mitochondrial disease are caused by AMP-activated protein kinase signaling. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
1
2
0 |
| 2.7.11.27 | Insulin Resistance |
17934342 |
Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKalpha. |
causal interaction
unassigned |
1
0 |
| 2.7.11.27 | Obesity |
18255222 |
AMPK and ACC phosphorylation: effect of leptin, muscle fibre type and obesity. |
causal interaction
therapeutic application
unassigned |
1
2
0 |
| 2.7.11.27 | Carcinoma |
18776129 |
Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
2
1
0 |
| 2.7.11.27 | Overnutrition |
18784329 |
Maternal overnutrition suppresses the phosphorylation of 5'-AMP-activated protein kinase in liver, but not skeletal muscle, in the fetal and neonatal sheep. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
1
0 |
| 2.7.11.27 | Hyperlipidemias |
18842111 |
Increased hepatic lipogenesis in insulin resistance and type 2 diabetes is associated to AMPK signaling pathway upregulation in Psammomys obesus. |
unassigned |
0 |
| 2.7.11.27 | Cysts |
19284883 |
Activation of an AMP-activated protein kinase is involved in post-diapause development of Artemia franciscana encysted embryos. |
diagnostic usage
unassigned |
3
0 |
| 2.7.11.27 | Ovarian Neoplasms |
19874425 |
Metformin attenuates ovarian cancer cell growth in an AMP- kinase dispensable manner. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
1
1
3
0 |
