EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.7.1.105 | Anemia |
1667653 |
Erythrocyte fructose 2,6-bisphosphate content in congenital hemolytic anemias. |
causal interaction
ongoing research
unassigned |
1
4
0 |
| 2.7.1.105 | Aortic Valve Stenosis |
19327508 |
Reduction of four-and-a-half LIM-protein 2 expression occurs in human left ventricular failure and leads to altered localization and reduced activity of metabolic enzymes. |
causal interaction
diagnostic usage
unassigned |
4
2
0 |
| 2.7.1.105 | Arthritis, Rheumatoid |
28239846 |
Inhibition of 6-phosphofructo-2-kinase suppresses fibroblast-like synoviocytes-mediated synovial inflammation and joint destruction in rheumatoid arthritis. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
3
1
0 |
| 2.7.1.105 | Breast Neoplasms |
26093295 |
Overexpression of miR-206 suppresses glycolysis, proliferation and migration in breast cancer cells via PFKFB3 targeting. |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
3
1
0 |
| 2.7.1.105 | Breast Neoplasms |
27613609 |
Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
3
4 |
| 2.7.1.105 | Carcinogenesis |
27079271 |
PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
3
4 |
| 2.7.1.105 | Carcinoma |
27239113 |
Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 2.7.1.105 | Carcinoma, Hepatocellular |
2841125 |
Rat hepatoma (HTC) cell 6-phosphofructo-2-kinase differs from that in liver and can be separated from fructose-2,6-bisphosphatase. |
ongoing research
unassigned |
4
0 |
| 2.7.1.105 | Carcinoma, Hepatocellular |
8549639 |
Characterization of the binding sites for [3H]glibenclamide in rat liver membranes. |
ongoing research
unassigned |
3
0 |
| 2.7.1.105 | Carcinoma, Hepatocellular |
9324310 |
Glucose response elements in a gene that codes for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
