EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.4.99.1 | Adenocarcinoma |
11001400 |
Clinical correlations of alpha2,6-sialyltransferase expression in colorectal cancer patients. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
3
1 |
| 2.4.99.1 | Adenocarcinoma |
31610800 |
Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
2
1 |
| 2.4.99.1 | Alzheimer Disease |
11698669 |
Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase. |
causal interaction
unassigned |
2
0 |
| 2.4.99.1 | Alzheimer Disease |
14507929 |
The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1. |
causal interaction
unassigned |
3
0 |
| 2.4.99.1 | Alzheimer Disease |
31724708 |
Disrupted glycosylation of lipids and proteins is a cause of neurodegeneration. |
causal interaction
unassigned |
4
0 |
| 2.4.99.1 | Arthritis, Rheumatoid |
19772356 |
Branch-specific sialylation of IgG-Fc glycans by ST6Gal-I. |
ongoing research
therapeutic application
unassigned |
3
2
0 |
| 2.4.99.1 | Arthritis, Rheumatoid |
29720252 |
Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 2.4.99.1 | Asthma |
30730306 |
Sialylation of MUC4? N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with Type-2 inflammation. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
4 |
| 2.4.99.1 | Astrocytoma |
33836687 |
Association of ST6GAL1 and CYP19A1 polymorphisms in the 3'-UTR with astrocytoma risk and prognosis in a Chinese Han population. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
4 |
| 2.4.99.1 | Atherosclerosis |
29654763 |
ST6GAL1 negatively regulates monocyte transendothelial migration and atherosclerosis development. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
1
4 |
