EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.4.2.28 | Adenocarcinoma of Lung |
31965001 |
MTAP-deficiency could predict better treatment response in advanced lung adenocarcinoma patients initially treated with pemetrexed-platinum chemotherapy and bevacizumab. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
1
4
4
0 |
| 2.4.2.28 | Adenoma |
19622299 |
[Expression of methylthioadenosine phosphorylase (MTAP) gene and demethylation of its promoter in human colorectal cancer.] |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
3
4
0 |
| 2.4.2.28 | Adenomatous Polyposis Coli |
33893330 |
Transition state analogue of MTAP extends lifespan of APCMin/+ mice. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
1
3
3 |
| 2.4.2.28 | Astrocytoma |
26088413 |
Expression of Methylthioadenosine Phosphorylase (MTAP) in Pilocytic Astrocytomas. |
unassigned |
0 |
| 2.4.2.28 | Astrocytoma |
33077924 |
Utility of methylthioadenosine phosphorylase immunohistochemical deficiency as a surrogate for CDKN2A homozygous deletion in the assessment of adult-type infiltrating astrocytoma. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
2
2
0 |
| 2.4.2.28 | Biliary Tract Neoplasms |
16373701 |
Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 2.4.2.28 | Breast Neoplasms |
3109530 |
Methylthioadenosine phosphorylase in human breast cancer. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 2.4.2.28 | Breast Neoplasms |
12438261 |
Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 2.4.2.28 | Carcinoma |
6411095 |
5'-deoxy-5'-methylthioadenosine phosphorylase--II. Role of the enzyme in the metabolism and antineoplastic action of adenine-substituted analogs of 5'-deoxy-5'-methylthioadenosine. |
ongoing research
unassigned |
4
0 |
| 2.4.2.28 | Carcinoma |
8616780 |
Codeletion of the genes for p16INK4, methylthioadenosine phosphorylase, interferon-alpha1, interferon-beta1, and other 9p21 markers in human malignant cell lines. |
diagnostic usage
ongoing research
unassigned |
1
2
0 |
