EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.4.1.226 | Atherosclerosis |
21284936 |
Correlation of C4ST-1 and ChGn-2 expression with chondroitin sulfate chain elongation in atherosclerosis. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 2.4.1.226 | Atherosclerosis |
30579596 |
Chondroitin sulfate N-acetylgalactosaminyltransferase-2 deletion alleviates lipoprotein retention in early atherosclerosis and attenuates aortic smooth muscle cell migration. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
2
0 |
| 2.4.1.226 | Atherosclerosis |
33504177 |
Chondroitin Sulfate N-acetylgalactosaminyltransferase-2 Impacts Foam Cell Formation and Atherosclerosis by Altering Macrophage Glycosaminoglycan Chain. |
causal interaction
ongoing research
unassigned |
1
4
0 |
| 2.4.1.226 | Brachydactyly |
21129727 |
Loss of CHSY1, a secreted FRINGE enzyme, causes syndromic brachydactyly in humans via increased NOTCH signaling. |
causal interaction
ongoing research
unassigned |
2
2
0 |
| 2.4.1.226 | Brachydactyly |
21129728 |
Temtamy preaxial brachydactyly syndrome is caused by loss-of-function mutations in chondroitin synthase 1, a potential target of BMP signaling. |
causal interaction
unassigned |
4
0 |
| 2.4.1.226 | Brachydactyly |
22280990 |
Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning. |
causal interaction
unassigned |
4
0 |
| 2.4.1.226 | Brachydactyly |
24269551 |
A novel CHSY1 gene mutation underlies Temtamy preaxial brachydactyly syndrome in a Pakistani family. |
unassigned |
0 |
| 2.4.1.226 | Brachydactyly |
27192887 |
A FURTHER PATIENT OF PURE 15q DELETION: CLINICAL AND MOLECULAR CYTOGENETIC FINDINGS. |
unassigned |
0 |
| 2.4.1.226 | Carcinogenesis |
30344756 |
CHSY1 promoted proliferation and suppressed apoptosis in colorectal cancer through regulation of the NF?B and/or caspase-3/7 signaling pathway. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
3
4 |
| 2.4.1.226 | Carcinoma, Hepatocellular |
28652022 |
CHSY1 promotes aggressive phenotypes of hepatocellular carcinoma cells via activation of the hedgehog signaling pathway. |
causal interaction
ongoing research
unassigned |
4
2
0 |
