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Results 1 - 10 of 6784 > >>
EC Number Disease PubMed ID Title of Publication Category Confidence Level
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acidosis 25085245 The SIRT1/HIF2? axis drives reductive glutamine metabolism under chronic acidosis and alters tumor response to therapy. therapeutic application
unassigned
4
0
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acquired Immunodeficiency Syndrome 22443029 New clinical findings on the longevity gene in disease, health, & longevity: Sirtuin 1 often decreases with advanced age & serious diseases in most parts of the human body, while relatively high & constant Sirtuin 1 regardless of age was first found in the hippocampus of supercentenarians. causal interaction
diagnostic usage
unassigned
2
2
0
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acquired Immunodeficiency Syndrome 28943955 p53 inhibits the upregulation of sirtuin 1 expression induced by c-Myc. causal interaction
diagnostic usage
ongoing research
unassigned
3
1
2
0
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acute Coronary Syndrome 25342474 Association between the SIRT1 mRNA Expression and Acute Coronary Syndrome. causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
4
1
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acute Kidney Injury 20139070 Kidney-specific overexpression of Sirt1 protects against acute kidney injury by retaining peroxisome function. causal interaction
ongoing research
therapeutic application
unassigned
2
4
2
0
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acute Kidney Injury 21416250 Cisplatin induces Sirt1 in association with histone deacetylation and increased Werner syndrome protein in the kidney. causal interaction
ongoing research
therapeutic application
unassigned
2
1
1
0
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acute Kidney Injury 23302720 The histone deacetylase, SIRT1, contributes to the resistance of young mice to ischemia/reperfusion-induced acute kidney injury. causal interaction
ongoing research
therapeutic application
unassigned
2
3
2
0
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acute Kidney Injury 24896770 Sirt1 deletion leads to enhanced inflammation and aggravates endotoxin-induced acute kidney injury. causal interaction
ongoing research
therapeutic application
unassigned
4
4
2
0
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acute Kidney Injury 25386563 Renal protective effect of sirtuin 1. causal interaction
ongoing research
therapeutic application
unassigned
3
2
1
0
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286Acute Kidney Injury 25607838 Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury. unassigned 0
Results 1 - 10 of 6784 > >>