EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
  2.3.1.257 | Carcinoma, Hepatocellular |
19695338 |
Patt1, a novel protein acetyltransferase that is highly expressed in liver and downregulated in hepatocellular carcinoma, enhances apoptosis of hepatoma cells. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
2
4 |
| 2.3.1.257 | Colonic Neoplasms |
26666750 |
Depletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathway. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
4
4 |
| 2.3.1.257 | Colonic Neoplasms |
30858358 |
NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
1
4 |
| 2.3.1.257 | Colorectal Neoplasms |
26666750 |
Depletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathway. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
4
4 |
| 2.3.1.257 | Colorectal Neoplasms |
30858358 |
NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
1
4 |
| 2.3.1.257 | Diabetes Mellitus |
31920356 |
Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase (NAMPT) and Sirtuin-1 (SIRT-1) Pathway in Obesity and T2DM: Modulation by Metformin and Macronutrient Intake. |
ongoing research
unassigned |
2
0 |
| 2.3.1.257 | Diabetes Mellitus, Type 2 |
31920356 |
Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase (NAMPT) and Sirtuin-1 (SIRT-1) Pathway in Obesity and T2DM: Modulation by Metformin and Macronutrient Intake. |
ongoing research
unassigned |
2
0 |
| 2.3.1.257 | Liver Neoplasms |
32942614 |
N-Terminal Acetyltransferases Are Cancer-Essential Genes Prevalently Upregulated in Tumours. |
causal interaction
diagnostic usage
unassigned |
4
1
0 |
| 2.3.1.257 | Liver Neoplasms |
34150665 |
Identification of NAA40 as a Potential Prognostic Marker for Aggressive Liver Cancer Subtypes. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
2
4 |
| 2.3.1.257 | n-terminal l-serine nalpha-acetyltransferase natd deficiency |
22231784 |
Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis. |
ongoing research
unassigned |
2
0 |
