EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
20674860 |
Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity. |
causal interaction
unassigned |
4
0 |
| 2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
22949503 |
Ablation of ALCAT1 Mitigates Hypertrophic Cardiomyopathy through Effects on Oxidative Stress and Mitophagy. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
2
0 |
| 2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
23150634 |
Metabolic interactions between the Lands cycle and the Kennedy pathway of glycerolipid synthesis in Arabidopsis developing seeds. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
25203315 |
ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
2
0 |
| 2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
26828064 |
Small Intestine but Not Liver Lysophosphatidylcholine Acyltransferase 3 (Lpcat3) Deficiency Has a Dominant Effect on Plasma Lipid Metabolism. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
1
4
0 |
| 2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
28846071 |
ER phospholipid composition modulates lipogenesis during feeding and in obesity. |
therapeutic application
unassigned |
2
0 |
| 2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
29673706 |
Lysophosphatidylcholine acyltransferase 3 deficiency impairs 3T3L1 cell adipogenesis through activating Wnt/?-catenin pathway. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
29866392 |
LPCAT3 deficiency in hematopoietic cells alters cholesterol and phospholipid homeostasis and promotes atherosclerosis. |
causal interaction
unassigned |
4
0 |
| 2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
30705887 |
Macrophage Lysophosphatidylcholine Acyltransferase 3 Deficiency-Mediated Inflammation Is Not Sufficient to Induce Atherosclerosis in a Mouse Model. |
causal interaction
ongoing research
unassigned |
1
3
0 |
| 2.3.1.23 | 1-acylglycerophosphocholine o-acyltransferase deficiency |
30838774 |
Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson's diseases. |
causal interaction
unassigned |
4
0 |
