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Results 1 - 10 of 33 > >>
EC Number Disease PubMed ID Title of Publication Category Confidence Level
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Adenocarcinoma 24928782 PME-1 modulates protein phosphatase 2A activity to promote the malignant phenotype of endometrial cancer cells. causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
2
4
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Alzheimer Disease 29281045 Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease. diagnostic usage
ongoing research
unassigned
1
2
0
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Alzheimer Disease 32341098 Reduced Expression of the PP2A Methylesterase, PME-1, or the PP2A Methyltransferase, LCMT-1, Alters Sensitivity to Beta-Amyloid-Induced Cognitive and Electrophysiological Impairments in Mice. causal interaction
therapeutic application
unassigned
1
3
0
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Astrocytoma 19293187 PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma. causal interaction
ongoing research
unassigned
4
4
0
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Carcinoma, Hepatocellular 32431540 Expression Pattern and Prognostic Utility of PME-1 in Patients with Hepatocellular Carcinoma. causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
2
2
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Endometrial Neoplasms 24928782 PME-1 modulates protein phosphatase 2A activity to promote the malignant phenotype of endometrial cancer cells. causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
2
4
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Endometrial Neoplasms 27048286 Inhibition of protein methylesterase 1 decreased cancerous phenotypes in endometrial adenocarcinoma cell lines and xenograft tumor models. causal interaction
ongoing research
therapeutic application
unassigned
4
1
4
0
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Glioblastoma 27810903 NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability. diagnostic usage
ongoing research
therapeutic application
unassigned
1
2
4
0
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Glioma 19293187 PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma. causal interaction
ongoing research
unassigned
4
4
0
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.233Glioma 27671680 PP2A Inhibitor PME-1 Drives Kinase Inhibitor Resistance in Glioma Cells. causal interaction
diagnostic usage
ongoing research
therapeutic application
2
2
2
4
Results 1 - 10 of 33 > >>