EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.1.1.127 | Carcinogenesis |
28639750 |
Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
1
1
0 |
| 2.1.1.127 | Carcinoma |
27285764 |
WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 2.1.1.127 | Carcinoma |
30319138 |
Overexpression of SET and MYND Domain-Containing Protein 2 (SMYD2) Is Associated with Tumor Progression and Poor Prognosis in Patients with Papillary Thyroid Carcinoma. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
4
0 |
| 2.1.1.127 | Carcinoma, Squamous Cell |
27285764 |
WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 2.1.1.127 | Infections |
25419628 |
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 2.1.1.127 | Influenza, Human |
25419628 |
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 2.1.1.127 | Intellectual Disability |
30171419 |
Identification of protoberberine alkaloids as novel histone methyltransferase G9a inhibitors by structure-based virtual screening. |
therapeutic application
unassigned |
1
0 |
| 2.1.1.127 | Leukemia |
23433670 |
Bromo-deaza-SAH: A potent and selective DOT1L inhibitor. |
therapeutic application
unassigned |
2
0 |
| 2.1.1.127 | Leukemia |
29694893 |
SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression. |
ongoing research
unassigned |
3
0 |
| 2.1.1.127 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
33931742 |
Targeting protein lysine methyltransferase G9A impairs self-renewal of chronic myelogenous leukemia stem cells via upregulation of SOX6. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
3
0 |
