EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.5.1.6 | Acute Kidney Injury |
32004633 |
Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2. |
therapeutic application
unassigned |
1
0 |
| 1.5.1.6 | Adenocarcinoma of Lung |
21779486 |
Epigenetic Silencing of ALDH1L1, a Metabolic Regulator of Cellular Proliferation, in Cancers. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
3
3
0 |
| 1.5.1.6 | Adenocarcinoma of Lung |
32481524 |
The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
4
0 |
| 1.5.1.6 | Astrocytoma |
19018242 |
Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypes. |
unassigned |
0 |
| 1.5.1.6 | Breast Neoplasms |
29868117 |
Deep Sequencing Revealed a CpG Methylation Pattern Associated With ALDH1L1 Suppression in Breast Cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
4
3
0 |
| 1.5.1.6 | Breast Neoplasms |
30774927 |
Regional methylome profiling reveals dynamic epigenetic heterogeneity and convergent hypomethylation of stem cell quiescence-associated genes in breast cancer following neoadjuvant chemotherapy. |
therapeutic application
unassigned |
4
0 |
| 1.5.1.6 | Carcinogenesis |
21987076 |
Decreased expression of ALDH1L1 is associated with a poor prognosis in hepatocellular carcinoma. |
causal interaction
diagnostic usage
unassigned |
4
4
0 |
| 1.5.1.6 | Carcinogenesis |
30362096 |
ALDH1L1 and ALDH1L2 Folate Regulatory Enzymes in Cancer. |
causal interaction
ongoing research
unassigned |
4
2
0 |
| 1.5.1.6 | Carcinogenesis |
34066916 |
Reply to Krupenko et al. Comment on "Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer Cancers 2020, 12, 1382". |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 1.5.1.6 | Carcinogenesis |
34203215 |
Knockout of Putative Tumor Suppressor Aldh1l1 in Mice Reprograms Metabolism to Accelerate Growth of Tumors in a Diethylnitrosamine (DEN) Model of Liver Carcinogenesis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
