EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.5.1.5 | Acidosis |
3877504 |
Increased activity of renal glycine-cleavage-enzyme complex in metabolic acidosis. |
unassigned |
0 |
| 1.5.1.5 | Anemia, Megaloblastic |
22108709 |
Update and new concepts in vitamin responsive disorders of folate transport and metabolism. |
causal interaction
unassigned |
4
0 |
| 1.5.1.5 | Anemia, Megaloblastic |
27707659 |
Precision Molecular Diagnosis Defines Specific Therapy in Combined Immunodeficiency with Megaloblastic Anemia Secondary to MTHFD1 Deficiency. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
4
2
0 |
| 1.5.1.5 | Anencephaly |
17035141 |
Neural tube defects and folate pathway genes: family-based association tests of gene-gene and gene-environment interactions. |
ongoing research
unassigned |
3
0 |
| 1.5.1.5 | Angina, Stable |
27872106 |
Methylenetetrahydrofolate Dehydrogenase 1 Polymorphisms Modify the Associations of Plasma Glycine and Serine With Risk of Acute Myocardial Infarction in Patients With Stable Angina Pectoris in WENBIT (Western Norway B Vitamin Intervention Trial). |
causal interaction
diagnostic usage
unassigned |
4
4
0 |
| 1.5.1.5 | Atherosclerosis |
20209990 |
[Features of allele polymorphism of genes involved in homocysteine and folate metabolism in patients with atherosclerosis of the lower extremity arteries] |
diagnostic usage
ongoing research
unassigned |
2
1
0 |
| 1.5.1.5 | Atypical Hemolytic Uremic Syndrome |
22108709 |
Update and new concepts in vitamin responsive disorders of folate transport and metabolism. |
causal interaction
unassigned |
4
0 |
| 1.5.1.5 | Breast Neoplasms |
24870594 |
Increased MTHFD2 expression is associated with poor prognosis in breast cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
4
0 |
| 1.5.1.5 | Breast Neoplasms |
33316375 |
Folate-mediated one-carbon metabolism: a targeting strategy in cancer therapy. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
2
4 |
| 1.5.1.5 | Carcinogenesis |
30343310 |
Methylenetetrahydrofolate Dehydrogenase 1 Silencing Expedites the Apoptosis of Non-Small Cell Lung Cancer Cells via Modulating DNA Methylation. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
4
0 |
