EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.3.1.3 | 3-oxo-5beta-steroid 4-dehydrogenase deficiency |
20522910 |
Characterization of disease-related 5beta-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency. |
causal interaction unassigned |
4 0 |
1.3.1.3 | Adrenoleukodystrophy |
30544401 |
Case report of dysregulation of primary bile acid synthesis in a family with X-linked adrenoleukodystrophy. |
causal interaction diagnostic usage ongoing research unassigned |
4 3 2 0 |
1.3.1.3 | Alagille Syndrome |
33476544 |
[Clinical characteristics and gene variants of patients with infantile intrahepatic cholestasis]. |
causal interaction unassigned |
3 0 |
1.3.1.3 | Arthritis, Rheumatoid |
28413214 |
Circulating Biomarkers for Predicting Infliximab Response in Rheumatoid Arthritis: A Systematic Bioinformatics Analysis. |
therapeutic application unassigned |
4 0 |
1.3.1.3 | Biliary Atresia |
9514540 |
Urinary 7alpha-hydroxy-3-oxochol-4-en-24-oic and 3-oxochola-4,6-dien-24-oic acids in infants with cholestasis. |
causal interaction diagnostic usage therapeutic application unassigned |
4 2 1 0 |
1.3.1.3 | Carcinoma, Hepatocellular |
28125709 |
Differential Feedback Regulation of ?4-3-Oxosteroid 5?-Reductase Expression by Bile Acids. |
causal interaction ongoing research unassigned |
1 4 0 |
1.3.1.3 | Carcinoma, Hepatocellular |
30769091 |
AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells. |
ongoing research unassigned |
4 0 |
1.3.1.3 | Carcinoma, Hepatocellular |
31330134 |
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease. |
causal interaction ongoing research unassigned |
4 4 0 |
1.3.1.3 | Carcinoma, Hepatocellular |
33493134 |
Diagnostic and prognostic values of AKR1C3 and AKR1D1 in hepatocellular carcinoma. |
diagnostic usage ongoing research therapeutic application unassigned |
4 1 1 0 |
1.3.1.3 | Carcinoma, Hepatocellular |
33502336 |
Differential activity and expression of human 5?-reductase (AKR1D1) splice variants. |
diagnostic usage ongoing research unassigned |
1 4 0 |