EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.17.4.2 | Acidosis, Lactic |
18504129 |
Mitochondrial DNA depletion syndrome due to mutations in the RRM2B gene. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 1.17.4.2 | Acquired Immunodeficiency Syndrome |
8078894 |
Inhibition of ribonucleotide reductase by 2'-substituted deoxycytidine analogs: possible application in AIDS treatment. |
therapeutic application
unassigned |
3
0 |
| 1.17.4.2 | Acute Kidney Injury |
24081220 |
Clofarabine-induced kidney toxicity. |
causal interaction
unassigned |
1
0 |
| 1.17.4.2 | Adenocarcinoma |
1385411 |
Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide. |
causal interaction
therapeutic application
unassigned |
4
2
0 |
| 1.17.4.2 | Adenocarcinoma |
2117605 |
Alterations of ribonucleotide reductase activity following induction of the nitrite-generating pathway in adenocarcinoma cells. |
unassigned |
0 |
| 1.17.4.2 | Adenocarcinoma |
7727399 |
Inhibition of ribonucleotide reductase by nitric oxide derived from thionitrites: reversible modifications of both subunits. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 1.17.4.2 | Adenocarcinoma |
12685191 |
Ribonucleotide reductase immunoreactivity in adenocarcinoma cells and malignant or reactive mesothelial cells in serous effusions. |
causal interaction
ongoing research
unassigned |
3
3
0 |
| 1.17.4.2 | Adenocarcinoma |
14555499 |
Ribonucleotide reductase subunit one as gene therapy target: commentary re: M-Y. Cao et al., Adenovirus-mediated ribonucleotide reductase R1 gene therapy of human colon adenocarcinoma. Clin. Cancer Res., 9: 4304-4308, 2003. |
ongoing research
therapeutic application
unassigned |
1
3
0 |
| 1.17.4.2 | Adenocarcinoma |
14661056 |
RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. |
causal interaction
unassigned |
3
0 |
| 1.17.4.2 | Adenocarcinoma |
16093443 |
Increased expression of the large subunit of ribonucleotide reductase is involved in resistance to gemcitabine in human mammary adenocarcinoma cells. |
causal interaction
unassigned |
1
0 |
