EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
    1.14.19.17 | Pancreatic Neoplasms |
29769046 |
?-Tocotrienol induces apoptosis in pancreatic cancer cells by upregulation of ceramide synthesis and modulation of sphingolipid transport. |
ongoing research
unassigned |
3
0 |
| 1.14.19.17 | Metabolic Diseases |
23547262 |
Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 1.14.19.17 | Neoplasms |
20628055 |
Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
4
0 |
| 1.14.19.17 | Neoplasms |
34217162 |
Association of the key genes in the pathophysiology between the Type 2 diabetes and Lung cancer. |
unassigned |
0 |
| 1.14.19.17 | Neoplasms |
23911762 |
Cationic ceramides and analogues, LCL30 and LCL85, as adjuvants to photodynamic therapy of tumors. |
ongoing research
unassigned |
2
0 |
| 1.14.19.17 | Neoplasm Metastasis |
27669432 |
Cell cycle-coupled expansion of AR activity promotes cancer progression. |
causal interaction
therapeutic application
unassigned |
3
2
0 |
| 1.14.19.17 | Neuroblastoma |
22377532 |
Cell density dependent reduction of dihydroceramide desaturase activity in neuroblastoma cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
3
1
0 |
| 1.14.19.17 | Hypertension |
22586587 |
Ceramide mediates vascular dysfunction in diet-induced obesity by PP2A-mediated dephosphorylation of the eNOS-Akt complex. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 1.14.19.17 | Hypertension |
27460939 |
Comparing nationwide prevalences of hypertension and depression based on claims data and survey data: An example from Germany. |
unassigned |
0 |
| 1.14.19.17 | Thrombosis |
21546100 |
Comparison of the safety between first- and second-generation drug eluting stents Meta-analysis from 19 randomized trials and 16,924 patients. |
causal interaction
therapeutic application
unassigned |
2
3
0 |
