EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.11.53 | Abortion, Habitual |
31281518 |
The m6A demethylase ALKBH5 controls trophoblast invasion at the maternal-fetal interface by regulating the stability of CYR61 mRNA. |
diagnostic usage
ongoing research
unassigned |
4
3
0 |
| 1.14.11.53 | Adenocarcinoma |
31906946 |
m6A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
2
1 |
| 1.14.11.53 | Adenocarcinoma of Lung |
31677788 |
ALKBH5-m6A-FOXM1 signaling axis promotes proliferation and invasion of lung adenocarcinoma cells under intermittent hypoxia. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
3
0 |
| 1.14.11.53 | Adenocarcinoma of Lung |
32849929 |
Identification of pathology-specific regulators of m6A RNA modification to optimize lung cancer management in the context of predictive, preventive, and personalized medicine. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
2
3 |
| 1.14.11.53 | Adenocarcinoma of Lung |
33934179 |
ALKBH5-mediated m6A demethylation of lncRNA RMRP plays an oncogenic role in lung adenocarcinoma. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
4
0 |
| 1.14.11.53 | Adenoma, Oxyphilic |
31985880 |
The N6 -methyladenosine (m6 A) erasers alkylation repair homologue 5 (ALKBH5) and fat mass and obesity-associated protein (FTO) are prognostic biomarkers in patients with clear cell renal carcinoma. |
diagnostic usage
ongoing research
unassigned |
4
3
0 |
| 1.14.11.53 | Adenomyosis |
32719721 |
m6A RNA Methylation Regulators Contribute to Eutopic Endometrium and Myometrium Dysfunction in Adenomyosis. |
causal interaction
diagnostic usage
unassigned |
3
1
0 |
| 1.14.11.53 | Aneurysm, Dissecting |
34490238 |
KIAA1429 and ALKBH5 Oppositely Influence Aortic Dissection Progression via Regulating the Maturation of Pri-miR-143-3p in an m6A-Dependent Manner. |
therapeutic application
unassigned |
1
0 |
| 1.14.11.53 | Arthritis, Rheumatoid |
32884942 |
Decreased ALKBH5, FTO, and YTHDF2 in Peripheral Blood Are as Risk Factors for Rheumatoid Arthritis. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
2
4
1
0 |
| 1.14.11.53 | Atherosclerosis |
28253220 |
Fat mass and obesity-associated protein attenuates lipid accumulation in macrophage foam cells and alleviates atherosclerosis in apolipoprotein E-deficient mice. |
causal interaction
ongoing research
unassigned |
1
3
0 |
