EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
12858176 |
Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. |
causal interaction unassigned |
2 0 |
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
15315958 |
11{beta}-Hydroxysteroid Dehydrogenase Type 1: A Tissue-Specific Regulator of Glucocorticoid Response. |
causal interaction therapeutic application unassigned |
3 2 0 |
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
15466942 |
11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. |
causal interaction therapeutic application unassigned |
3 2 0 |
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
15827106 |
A study of the hexose-6-phosphate dehydrogenase gene R453Q and 11beta-hydroxysteroid dehydrogenase type 1 gene 83557insA polymorphisms in the polycystic ovary syndrome. |
ongoing research unassigned |
2 0 |
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
15956339 |
Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1. |
causal interaction unassigned |
4 0 |
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
16091483 |
Genotypes at 11beta-hydroxysteroid dehydrogenase type 11B1 and hexose-6-phosphate dehydrogenase loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample. |
causal interaction unassigned |
3 0 |
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
17062770 |
Lack of Association of the 11beta-hydroxysteroid dehydrogenase type 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen production, blood pressure, glucose metabolism, and dementia. |
causal interaction ongoing research therapeutic application unassigned |
3 2 1 0 |
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
18628520 |
Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency. |
causal interaction unassigned |
4 0 |
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
19935835 |
Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis. |
causal interaction therapeutic application unassigned |
3 4 0 |
1.1.1.47 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency |
21050867 |
Mutations of the hexose-6-phosphate dehydrogenase gene rarely cause hyperandrogenemic polycystic ovary syndrome. |
causal interaction unassigned |
3 0 |