EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.1.1.213 | Adenocarcinoma |
11925926 |
[Gene expression profiling of human ovarian epithelial tumors by digo nucleotide microarray] |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 1.1.1.213 | Adenocarcinoma |
16886619 |
Expression of dihydrodiol dehydrogenase and resistance to chemotherapy and radiotherapy in adenocarcinoma cells of lung. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
4
0 |
| 1.1.1.213 | Breast Neoplasms |
15492289 |
Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
3 |
| 1.1.1.213 | Breast Neoplasms |
17950253 |
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 1.1.1.213 | Carcinoma |
9415401 |
Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
4
0 |
| 1.1.1.213 | Carcinoma |
9716498 |
Sequence of the cDNA of a human dihydrodiol dehydrogenase isoform (AKR1C2) and tissue distribution of its mRNA. |
ongoing research
unassigned |
4
0 |
| 1.1.1.213 | Carcinoma |
11842089 |
Increased expression of dihydrodiol dehydrogenase induces resistance to cisplatin in human ovarian carcinoma cells. |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
3
4
0 |
| 1.1.1.213 | Carcinoma |
11925926 |
[Gene expression profiling of human ovarian epithelial tumors by digo nucleotide microarray] |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 1.1.1.213 | Carcinoma |
15138708 |
Ubiquitous induction of resistance to platinum drugs in human ovarian, cervical, germ-cell and lung carcinoma tumor cells overexpressing isoforms 1 and 2 of dihydrodiol dehydrogenase. |
causal interaction
ongoing research
unassigned |
4
4
0 |
| 1.1.1.213 | Carcinoma |
15197778 |
Inverse expression of dihydrodiol dehydrogenase and glutathione-S-transferase in patients with esophageal squamous cell carcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
