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EC Number
Disease
PubMed ID
Title of Publication
Category
Confidence Level
Osteoarthritis
Current and emerging therapeutic strategies for preventing inflammation and aggrecanase-mediated cartilage destruction in arthritis.
causal interaction
1
Osteoarthritis
The development and characterization of a competitive ELISA for measuring active ADAMTS-4 in a bovine cartilage ex vivo model.
causal interaction
3
Neoplasm Metastasis
Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively.
causal interaction
2
Hydronephrosis
A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-1 null mutant mice develop renal lesions mimicking obstructive nephropathy.
causal interaction
2
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Identification of genetic variants associated with skeletal muscle function deficit in childhood acute lymphoblastic leukemia survivors.
causal interaction
3
Colorectal Neoplasms
ADAMTS expression in colorectal cancer.
causal interaction
3
Osteoarthritis
Discovery of (1S,2R,3R)-2,3-Dimethyl-2-phenyl-1-sulfamidocyclopropanecarboxylates: Novel and Highly Selective Aggrecanase Inhibitors.
causal interaction
2
Neoplasm Metastasis
The carboxyl-terminal half region of ADAMTS-1 suppresses both tumorigenicity and experimental tumor metastatic potential.
causal interaction
4
Cardiovascular Diseases
The role of serum ADAMTS-1 and aggrecan on polycystic ovary syndrome in adolescents and younger-aged females.
causal interaction
1
Colorectal Neoplasms
Promotion of Tumor Growth by ADAMTS4 in Colorectal Cancer: Focused on Macrophages.
causal interaction
4
Results 1 - 10 of 811 > >>