EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   3.4.24.82 | Acute Coronary Syndrome |
19944557 |
ADAMTS4 level in patients with stable coronary artery disease and acute coronary syndromes. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 3.4.24.82 | Arthritis |
11311239 |
Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4). |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.4.24.82 | Arthritis |
12020478 |
Aggrecanase-mediated cartilage degradation. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.4.24.82 | Arthritis |
12755694 |
Selective inhibition of ADAMTS-1, -4 and -5 by catechin gallate esters. |
causal interaction
unassigned |
1
0 |
| 3.4.24.82 | Arthritis |
15880348 |
ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
2
4
0 |
| 3.4.24.82 | Arthritis |
17487981 |
Substrate-dependent inhibition kinetics of an active site-directed inhibitor of ADAMTS-4 (Aggrecanase 1). |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 3.4.24.82 | Arthritis |
17546624 |
Interleukin-4 antagonizes oncostatin M and transforming growth factor beta-induced responses in articular chondrocytes. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 3.4.24.82 | Arthritis |
19342688 |
Adaptor proteins and Ras synergistically regulate IL-1-induced ADAMTS-4 expression in human chondrocytes. |
causal interaction
therapeutic application
unassigned |
4
3
0 |
| 3.4.24.82 | Arthritis |
26025392 |
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.4.24.82 | Arthritis |
27301579 |
Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
4
0 |
